Thursday, October 31, 2019

Comparative character analysis Research Proposal

Comparative character analysis - Research Proposal Example The reason for Paul and Dave’s sense of entrapment stems from their lack of social and economic power. While Paul was born to a middle-class worker who had â€Å"a worthy ambition to come up in the world†, Dave was condemned to the life of a farm laborer. Disillusioned by their surroundings, both of them felt the need to salvage their situation. Whereas Paul thought money could transform his identity, Dave was misled to believe that owning a gun could help him earn respect. Though both Paul and Dave share a common goal - to rise above their ordinary existence, they end up adopting different means to achieve it. Whereas Dave sweet talks his mother into giving him the two dollars required to buy the gun, Paul does something drastic – he steals one thousand dollars. These different actions cast both of them in different lights. The reader finds Dave childish in his strategy for getting a gun. â€Å"Mebbe Ma will lemme buy one when she gits mah pay from ol man Hawkins,† Dave speculates, sounding every bit a boy as he resolves, â€Å"Ahma beg her t gimme some money.† After he procures the gun, he is mighty careful in hiding it. Later, when he is overcome by the desire to hold it, he makes sure that he is safe and he plows â€Å"two whole rows before he decide[s] to take out the gun† . He then casts careful glances in all directions and then after being sure that he is not being watched, carefully unfastens the gun from his leg, a nd proudly flashes it before the mule: â€Å"Know whut this is, Jenny? Naw, yuh wouldn know! Yuhs jusa ol mule! Anyhow, this is a gun, n it kin shoot, by Gawd!† . He promptly then issues a warning to Jenny: â€Å"When Ah pull this ol trigger, Ah don wan yuh t runnacka fool now!†. It is an irony that he tells Jenny exactly what he should be paying heed to. The silly words that Dave utters, only amuses the reader and they instantly

Tuesday, October 29, 2019

Miscarriages of Justice Essay Example | Topics and Well Written Essays - 1000 words

Miscarriages of Justice - Essay Example This happens because of inefficient procedures . Second, the laws that are applied to them. Third, for there is no information that justifies the applied treatment or punishment. Fourth, if suspects, defendants or convicts are handled unfavorably by the state to an unequal extent compared with the necessity to protect the rights of others; or, fifth, if the rights of other persons are not effectively or equally protected or defended by State action against law violators or, sixth, by State law itself(Greer, 1986). For, the six groups above revolve around themes of breach of rights of suspects and defendants, the disproportionate treatment of suspects/defendants or the non-vindication of the rights of victims, might be termed direct miscarriages. In addition, it may be possible to derive from their infliction a seventh, indirect miscarriage which affects the community as a whole. A belief coming out of deceit or illegalities will corrode the state's claims to legitimacy. For, this is founded on the community criminal justice system's values which includes as respect for individual rights. In this way, as well as the unwanted faith of the individual, the "moral integrity of the criminal process" suffers harm(McConville, 1994). Also, there could be a common detriment by way of diminished confidence in the vanguards of law and order leading to lesser active citizens aiding the police and a decrease in the number of jurors willing to convict even the glaringly "guilty".Definitely, it has been deba ted that this indirect form of miscarriage can exist independently as well as contingently in two respects. One is that a breach of "the principle of judicial legitimacy" should be of concern even if there is an accurate and fair determination of guilt or innocence. Secondly, it still produces great moral harm even if, so far as the individual is concerned, there is an error but no real harm is inflicted (say, when a person imprisoned for life is wrongfully convicted soon afterwards of a minor motoring offence). It is therefore argued that the State itself should avoid actions or processes which might damage the integrity of the system. Consistent with this concern, lawyers, whether acting for prosecution or defence, are reminded that they are not the ciphers of their clients but owe duties of integrity to the criminal justice system(Poole, 1998). Critical examination why gender related crime is important to understanding relevant policies of the criminal justice policyIn the article stated that the gender equality duty and the criminal justice system April 2007: The Gender Equality Duty comes in to force, the gender equality duty has been the biggest radical metamorphosis to sex to sex discrimination law for the past thirty years. It is also similar to the introduction in 2001 of a similar public sector race equality duty after the Stephen Lawrence Inquiry and the introduction of a disability equality duty in December 2006. Furthermore, Fawcett publications of the Fawcett Society had published two reports to support the implementation of the Gender Equality Duty in the criminal justice system: The responsibility to understanding the "understand your duty" section details how the law should affect the criminal just

Sunday, October 27, 2019

Genetic Screening: Types of Tests and Applications

Genetic Screening: Types of Tests and Applications GENETIC SCREENING AOUDUMBARI B.DESAI What is Genetic Screening? Genetic screening is a process in which DNA is tested to check if a person has any genetic indicators of diseases. It can also be defined as an experimental technique used for identification and selection of individual who possess phenotype of our interest in a mutangenized population. Thus genetic screening can also be called as phenotypic screening. It helps us to provide a better insight of functioning of gene in an individual. It has got applications in various genome project. The functioning of gene can be well determined by Forward genetic screen or Reverse genetic screen. Forward genetic screening first approaches towards the phenotype and then moves towards identifying genes i.e, genes responsible for a particular phenotype in an individual is identified. Whereas in reverse genetic screen it starts with gene or set of genes and moves towards analyzing the resultant phenotype by assaying its effect of disruption. A defined genetic background of organism being used and constant experimental procedure for identification of mutants of interest are the two key component of successful forward genetic screening. Define genetic background helps to identify and locate affected genes in mutant individual with greater efficiency (Herman .R.K, et al.,2005). Many a times genetic screening and genetic testing are considered to be a common terms, however there is difference between genetic screening and testing. Genetic screening is a technique in which set of diagnostics test are used on large number of individuals to test these individuals who are at high risk of genetic disorders and are the carriers of that specific genes, whereas genetic testing uses different laboratory test to identify the genetic status of individual. The individuals who are already suspected to be at a higher risks for a particular genetic disorder undergo the genetic testing. It is based on medical history of family or on screening tests. But the similarity between both the test is both of them undergo laboratory tests to identify the presence of specific genes which may cause genetic disorders. Genetic screening is a term that is also encountered in prenatal screening with pregnant women. Many researcher do screening on a broad spectrum in large number of people to find potential for genetic diseases. Nowadays genetic screening is also used by health insurance companies to screen the people for genetic disorders and avoid paying extra money. Genetic screening also include newborn genetic screening to identify new born who would benefit from early treatment. Reproductive genetic screening is also done to help reproductive decision making, and in this family history of the patient is checked to identify individuals who would get added benefit from additional prevention measure. Types of screening variation There are different screening variations which are used to identify genes that cause a mutants in phenotype of interest. Some of them are as follows : Enhancer Enhancer screening is used to screen an mutant individual with known genetic mutation. It can further be used to screen an individual with additional gene mutations that has its major role in biological and physiological processes. It is the mutation in one genes that causes the intensification of phenotype resulted due to mutation in another gene. The genetic enhancer screening identifies a mutations which enhance aphenotype of interest in already mutant individual. Source http://www.wormbook.org/chapters/www_geneticenhancers/geneticenhancers.html Synthetic interaction betweenmec-8andsym-3.(A) Themec-8; sym-3double mutant has a highly penetrant defect: the anterior tip (arrow) of the pharynx is not properly joined to the anterior tip of the body (arrowhead), and a functional mouth is not formedThe mutants also have a bulbous nose, an enlargement of the anterior-most part of the body, which is particularly evident in the example shown here. The junction of the pharynx and anterior end of the body is normal in thesym-3single mutant (B) and in themec-8single mutant (C). Suppresor It is used to identify the suppressor mutations. Suppressor mutations revert the original mutations. It can be defined as the one which suppresses the phenotype of original mutations and are the another mutations on the site of chromosome which are distinct from the mutation under study. It has an intragenic suppression and extragenic suppression. Intragenic suppression is the one in which mutation is in same gene as in original mutation.whereas if there is a mutation in different gene then it is called as extragenic suppression or intergenic suppression. Temperature sensitive It is a type of screening technique which involves performing temperature shifts to enhance a mutant shift. The organism grown at a lower temperature will have normal phenotype whereas at higher temperature the mutation in that particular gene will make it unstable. For example Lee Hartwell and Paul nurse independently carried out temperature sensitive screening to identify mutants defective in cell cycle S.cerevisiae and S.pombe. Types of Genetic Screening : Presymptomatic screening Carrier screening parental screening, newborn screening, carrier screening, forensic screening and susceptibility screening. Presymptomatic screening is used to screen the patients whose health is in danger. Carrier screening is used to carry out the analysis of individuals with a gene or a chromosome abnormality that may cause problems either for offspring or the person screened.it is carried out in healthy individuals where there can be a risk of genes harmful to offsprings or future generation. This can be done by testing of blood or tissue samples and can show the presence of a particular genetic trait, changes in chromosomes, or changes in DNA that are associated with inherited diseases in asymptomatic individuals. For example carrier screening is done for sickle cell anemia, Tay-Sachs disease, duchenne muscular dystrophy, hemophilia, Huntingtons disease, and neurofibromatosis. Prenatal screening is carried out in a fetus when it is at risk for various identifiable genetic diseases or traits. It began in 1966. Newborn screening is related with the analysis of blood or tissue samples taken in early infancy in order to detect genetic diseases for which early intervention can avert serious health problems or death. Newborn screening was started in 1960 with the ability to test newborns for a rare metabolic disease, phenylketonuria (PKU). Two other examples of newborn screening are the testing of African American infants for sickle cell anemia and Ashkenazic Jews for Tay-Sachs disease. Forensic screening is used in criminal investigations it is used to to discover a genetic linkage between suspects and evidence discovered in criminal investigations. As DNA of each and every person is unique, many people are reluctant to see such information become part of any national database, which might include information not only about identity but also about proclivity toward disease or behavior. Susceptibility screening is a technique which is used to screen a selected population for genetic susceptibility to environmental hazards. It helps in the identification of workers who may be susceptible to toxic substances that are found in their workplace and may cause future disabilities. Types and Uses of Genetic Tests Source :- Norrgard.K., 2008 http://www.nature.com/scitable/topicpage/medical-careers-genetic-screening-and-diagnostics-639 Purpose of genetic screening Genetic screening acts as an important tool in modern preventive medicine. It is used to confirm the diagnosis in patients with symptoms. Genetic screening also helps to advise other family members of the diagnosed patient to detect whether they also have the disease or have genetic markers for the disease even if they dont have symptoms ,and also to check whether they are carriers or are neither. It also helps in detecting when one partner is a sufferer or carrier, to test the other partner in order to advise whether their child will have the disease, be a carrier or will not have the disease. If diseases observed in both the parents, the child must inherit the disease or the genetic markers for the disease. It may happen that one parent has the disease and the other partner also has the genetic markers for it but there are no symptoms for it, therefore the child may develop the disease or alternatively may not show any symptoms during its lifetime. If one parent has the disease and the other is a carrier, in each pregnancy there is a 50:50 chance of the child inheriting the disease. In the population, screening is carried out to discover undiagnosed sufferers or those with genetic markers for the disease, to discover carriers and to aid research into the prevalence and severity of the disease and the carrier ratio. Maternal serum alpha-fetoprotein (MSAFP) screening, enhanced MSAFP, amniocentesis, chorionic villus sampling (CVS), percutaneous umbilical blood sampling (PUBS),fetal biopsy and fetal cell sorting are some of the genetic screening tests which are currently available for pregnant women. MSAFP is a blood-screening test. It is performed at the 16-18 week gestation date and it tests for spina bifida. Enhanced MSAFP is also a similar type of blood-screening test that measures levels of certain biochemical markers to test for the presence of Downs syndrome. But the only thing is that this test only has an accuracy of 60-65%. Amniocentesis is performed at the 16-18 week of gestation. Amniocentesis uses amniotic fluid to test for chromosomal abnormalities. It is also used to find biochemical abnormalities at the genetic level, it helps in detecting up to 180 genetic disorders. CVS i.e, chorionic villus sampling screening is performed at 10-12 weeks into gestation and it uses chorion tissue f or chromosomal analysis in biochemical and DNA studies. It is not widely used because this test has a drawback of correlation to produce newborns with limb abnormalities. ).Percutaneous umbilical blood sampling, PUBS is performed after week 18 . PUBS is used only as a confirmation test based on results from previous other tests. In fetal tissues are taken for DNA testing . Fetal cell sorting includes an experimental procedure in whcich blood is taken from mother and fetal cells are tested in mothers blood. Oberle,I. D. Camerino.G, 1985 carried out genetic screening for hemophilia A(classic hemophilia) with polymorphic DNA probe. They collected blood samples after informed consent from13 families and carried out coagulation and immunologic assay. In this experiment they develop a new technique to screen the patients for hemophiliaA in the families at risk for the disease. A DNA probe (St14) that detects a very polymorphic region on the human X chromosome has been shown to be closely linked to hemophilia A. They observed that there was no recombination between the St14 locus and hemophilia A in 12 families studied. The odds in favor of linkage are 4.4 x 109to 1 (lod score, 9.65). They found that there was 0 to 6.5% probability of the 95 per cent confidence interval of a recombination between St14 and hemophilia A. This informative DNA probe which causes families in risk of hemophilia A in more than 90 per cent, can be used in conjunction with classic biologic assays to identify carriers with an accuracy of 96 per cent or more. If a small risk of misclassification due to crossover between the test and the disease loci is accepted, this DNA marker should allow first-trimester prenatal diagnosis of hemophilia A. Segregation analysis with St14 may thus represent a major improvement in genetic counseling for hemophilia A. Social dilemmas of genetic screening Though genetic screening is beneficial to society it has a got lot of controversies because by using genetic marker to check for genetic disorders is definitely beneficial to society because due to early diagnosis a preventive symptom treatment can be given by early medical assisantnce but however many a times it is observed that if a genetic disorder is detected in fetus then fetus is readily aborted. So here a controversy comes because no one has got right to end anyones life. Also many a times it happens that individuals carrying a genetic disorder or diseases are being discriminated by society or by health insurers and employers. Hence this genetic screening has brought up a new legal, social and ethical dilemmas. References Karthikeyan. M.1999, Human Genetic Screening, http://www.ndsu.edu/pubweb/~mcclean/plsc431/students99/karthikeyan.htm Norrgard.K., 2008, Medical Careers: Genetic Screening and Diagnostics, Nature Education1(1): pg no- 92 http://www.nature.com/scitable/topicpage/medical-careers-genetic-screening-and-diagnostics-639 Burke.W., et al., 2011, Genetic Screening , Epidemologic reviews Oxford journal 33(1): pg no- 148–164Â  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166195

Friday, October 25, 2019

Shelley Jacksons Patchwork Girl Essay example -- Shelley Jackson Patc

Shelley Jackson's Patchwork Girl Patchwork Girl, a hypertext vision sewn together by Shelley Jackson, is a story and an account of the creation of a monster and the relationship the mind has with the monster within the technical boundary of lexia. The monster metaphorically was originally created by Mary Shelley in Frankenstein, but has now resurfaced in a layered identity with an opposing forum of complexity. Jackson has designed her version of the timeless tale from the female perspective by offering the reader not only a facet into the monster’s mind, but that of Mary’s, the girl’s, and of the author’s, which accounts for three female angles of perception. Through each narrative voice (and/or lexia), the reader discovers the psychological nightmare of mental maturity and the pains of achieving the ultimate sense of creativity or life. For Mary it is the obsession of the creation of life and the dedication to keep a promise, while for the girl and the monster it is the aspect of finding the understanding and acceptance in a stitched life. However, for Shelley Jackson the nightmare is the hyper literary challenge of stitching together thought and creation in fictional prose to show the relationship of mother to child or writer to the word by the means of technology. The Hypertext fiction Patchwork Girl is offered with three primary story lines in lexia story format, which is effectively connected or stitched together to reveal the lives of Mary, Shelley, the girl, and the monster from the creative impulse of the mind’s imagination visually represented in a non-linear string of links. As the reader or in this case user enters the hypertextual world of Shelley Jackson’s words, the initial question, "Where should I begin," ... ...readers or audience a compelling story, visual stimulation, various inter-linked story progression, unlimited path access, complex thematic motives, and unpredictability of discovery. For these reasons alone, it can be assumed that hypertext fiction will intrigue itself into the spectrum of popular culture and with that establish a longevity, which may surpass previous forms of literary media. Works Cited and Consulted Hayles, N. Katherine. "Simulating Narratives: What Virtual Creatures Can Teach Us." Critical Inquiry 26 (1999): 1-26. ---. "Virtual Bodies and Flickering Signifiers." How We Became Posthuman: Virtual Bodies in Cybernetics, Literature, and Informatics. Chicago: University of Chicago Press, 1999. 25-49. Jackson, Shelley. Patchwork Girl by Mary/Shelley and herself. Watertown, MA: Eastgate Systems, 1995. Electronic. .

Thursday, October 24, 2019

Beijing bicycle

Juxtaposition is used to frame the main ideas in Xiaoshuai's Beijing Bicycle meaning the bicycle of a seven teen year old, was its original name in Chinese when it was titled â€Å"Beijing Bicycle† later. Juxtaposition is being used by Xiahoshuai to make the audience recognize the main idea's of this film. The main ideas of this film was conflict between Urban and Rural culture, clash of traditional with the contemporary, and how China is beginning to develop into a modern society. Guei and Jian are characters in this film and are used to represent conflicts between rban and rural culture.Background scenes are also used to contrast modern and old China and how it is being changed. Chinese ancient alley ways are seen in many parts of the movie. Because these alley ways have been there for a long time, it is considered as an ancient pathway. The houses which can also be seen are built in the old time and the architecture is old fashioned. Construction sites can also be seen at t he start of the movie, down below we can see the ancient alley ways and cars passing by. This shows how China is beginning to change into a new country where everything is developed.Ancient alley ways can also symbolize how China is turning into a developed country, since these designs are starting to disappear. When Guei and Jian are running away they run through these ancient alley ways and meet up each time, this proves how ancient alley ways might be overwhelmed by the modernization of China and disappearing slowly. Guei comes from the country side and Jian is from the city. 2 characters with totally different cultural background are being used to contrast urban and rural life. However they both have one thing in common, which is the importance of the bike to them.To Guei the bicycle represents his lively hood and his Job; he protects the bike with all his strength. The bicycle symbolizes pride, status to Jian; he hides the bike because he may feel guilt and does not want to sho w it. Guei as a country boy is amazed at the view of Beijing; however he gets bullied by Jian's friends and cannot protect himself or the bicycle. His characteristics changed at the last scene where he used the rock to hit the person who was wrecking his bike, like Jian hit his ex-girlfriends new boyfriend. This may symbolize how Guei is slowly adapting to the city.Jian is a dynamic character in this film; at the beginning he seems ignorant and when his bicycle was stolen his friends always backed him up. However as the story progresses we can see some change happening when he introduces himself go Guei. At the end scene when they were being chased, Jian tells Guei to get away from him and when they both reach at a dead end â€Å"Get out of here† Jian says that to Guei because he doesn't want to get him in trouble. This symbolizes friendship and Jian's character development because he is trying to protect Guei and doesn't want him to get beaten.This may portray how China is c hanging into a different country where it cares about its surroundings, Just like Jian's character develops into a person who can fght for himself and cares about Guei. Xiaoshuai's main idea of the film was to show how China is beginning to develop into a modern city and becoming more independent. His use of Juxtaposition China and how traditional China is moving towards modern China. As China is becoming developed so as the people in China no matter where that person is from he/she is participating in this huge change.

Wednesday, October 23, 2019

Further Oral Proposal

12th Grade IB Further Oral Activity Proposal Due Date: November 5th 1. Describe the primary text for your presentation. What type of text is it? What is its origin? Who created the text? (2 points) Our text is 3 different songs from three different artists. The first one is â€Å"Get Up† by 50 Cent. The second one is â€Å"Grenade† by Bruno Mars. The third one is â€Å"La La La† by Snoop Lion. 2. Complete the following chart for your primary text. Make sure you answer all of the questions provided. (2 x 5 points) Audience / purpose: ? Who does the text target?The first two songs may be directed to a younger audience. The second song’s audience may especially be romantic or heart-broken people. The third song is written for everyone. ? What does the author wish to achieve through the text? 50 Cent tries to show off about his way of life. Bruno Mars tries to be romantic and depicts his love life. Snoop Lion tries to affect people. Content / theme: ? How does the content of the text relate to the overarching themes of the unit (Language and Power, Language and Identity, Language and Gender)?The texts relate to theme of Language and Culture. They might also be related to the theme of Language and Gender. Tone / mood: ? What is the attitude about the subject of the text? How is this achieved? 50 Cent is more aggressive and bossy. Bruno Mars is emotional, questioning and dreamy. ? Describe the atmosphere of the text. How is this achieved? In â€Å"Get Up†, you feel pressured and weaker as 50 Cent keeps giving orders and shows off. Bruno Mars makes you feel emotional as well.He depicts the contrast between the woman’s lack of interest to his romance. Stylistic devices: ? How does the author use language to convey a sentiment or message? ? What type of language is used (dialect, jargon, accent, diction)? ? How is imagery created? ? Does the text contain any of following: irony, sarcasm, rhetorical devices, figurative language, analogy, musical qualities, etc? Structure: ? How is the text organized (i. e. layout/ formatting)? ?What kinds of structural elements of a particular text type do you see? . Provide an outline for your presentation. (8 points) One of the songs will be played in class. It’s video can be shown as well. Then, if necessary or interesting or related to the song, the background and culture of the artist will be shared with the class. Then the lyrics will be analyzed and a connection will be made between the language in the song and the artist’s culture. After that, the second and third songs will be presented the exact same way

Tuesday, October 22, 2019

How to Write in MLA Style

How to Write in MLA Style On this episode, we discuss MLA style, including what it is, who uses it in their research, some important things to remember when writing a paper in MLA format, whats new in the 8th Edition of the MLA Handbook, and how to format in-text citations and a works cited page.MLA style is often used by scholars in the humanities and the liberal arts. The humanities and the liberal arts consist of subjects like English literature, rhetoric and composition, cultural studies, and foreign language studies and literature.You will probably use MLA style if you are writing a literary analysis, a persuasive essay, a literary criticism, an expository essay, or a research paper for the humanities.In addition to these topics, we cover:A few things to remember when using MLA style, such as keeping 1-inch margins on all sides.Whats changed in the 8th Edition, for example, how MLA has been adapted for digital research.The format of in-text citations, and how they are needed if you are paraphrasing or di rectly quoting a source.How to complete a page, including how the second and subsequent lines are indented.